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[51] During clinical trials, the common side effects affecting more than one in 10 people are (in order of frequency): pain and swelling at the injection site, tiredness, headache, muscle aches, chills, joint pain, fever or diarrhea

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doi:10.3945/an.117.015628

Tricyclic antidepressants, such as cyclobenzaprine are dosed at 520 mg or nortriptyline, initiated at a dose of 10 mg at bedtime, while SNRIs like duloxetine and venlafaxine are started at 30 mg and 37.5 mg daily, respectively, titrated to a maximum of 50% of that used in non-cirrhotic population